2gej

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Image:2gej.png

Template:STRUCTURE 2gej

Crystal Structure of phosphatidylinositol mannosyltransferase (PimA) from Mycobacterium smegmatis in complex with GDP-Man

About this Structure

2GEJ is a 1 chain structure of sequence from Mycobacterium smegmatis. Full crystallographic information is available from OCA.

Reference

  • Guerin ME, Buschiazzo A, Kordulakova J, Jackson M, Alzari PM. Crystallization and preliminary crystallographic analysis of PimA, an essential mannosyltransferase from Mycobacterium smegmatis. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 May 1;61(Pt, 5):518-20. Epub 2005 Apr 22. PMID:16511084 doi:10.1107/S1744309105012364
  • Kordulakova J, Gilleron M, Mikusova K, Puzo G, Brennan PJ, Gicquel B, Jackson M. Definition of the first mannosylation step in phosphatidylinositol mannoside synthesis. PimA is essential for growth of mycobacteria. J Biol Chem. 2002 Aug 30;277(35):31335-44. Epub 2002 Jun 14. PMID:12068013 doi:10.1074/jbc.M204060200
  • Briken V, Porcelli SA, Besra GS, Kremer L. Mycobacterial lipoarabinomannan and related lipoglycans: from biogenesis to modulation of the immune response. Mol Microbiol. 2004 Jul;53(2):391-403. PMID:15228522 doi:10.1111/j.1365-2958.2004.04183.x
  • Nigou J, Gilleron M, Puzo G. Lipoarabinomannans: from structure to biosynthesis. Biochimie. 2003 Jan-Feb;85(1-2):153-66. PMID:12765785
  • Coutinho PM, Deleury E, Davies GJ, Henrissat B. An evolving hierarchical family classification for glycosyltransferases. J Mol Biol. 2003 Apr 25;328(2):307-17. PMID:12691742

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