1mem

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1mem, resolution 1.8Å

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CRYSTAL STRUCTURE OF CATHEPSIN K COMPLEXED WITH A POTENT VINYL SULFONE INHIBITOR

Disease

Known disease associated with this structure: Pycnodysostosis OMIM:[601105]

About this Structure

1MEM is a Single protein structure of sequence from Homo sapiens with BZP and BNS as ligands. Active as Cathepsin K, with EC number 3.4.22.38 Structure known Active Site: CAT. Full crystallographic information is available from OCA.

Reference

Crystal structure of human cathepsin K complexed with a potent inhibitor., McGrath ME, Klaus JL, Barnes MG, Bromme D, Nat Struct Biol. 1997 Feb;4(2):105-9. PMID:9033587

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