Molecular Playground/Glutamate Receptor

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A CBI Molecule being studied in the University of Massachusetts Amherst Chemistry-Biology Interface Program at UMass Amherst and on display at the Molecular Playground.




Glutamate Receptor

Drag the structure with the mouse to rotate

Glutamate Receptor

Full view of the glutamate receptor shows the overall structure (amino-terminal, ligand-binding and transmembrane domains) in both ()(MF) and () models.


Zooming in at the top of the receptor () one can view the amino terminal domain, which is a part of the extracellular domain. This domain is implicated in receptor assembly, trafficking, and localization.


Moving toward the bottom of the receptor () one can view the transmembrane domain.


This view () highlights the area where a receptor antagonist, 2K200225, will bind.


Close up view of the ligand binding site () of the nature ligand glutamate.



Molecular Playground banner: A receptor involved in excitatory neurotransmission. It's so pretty!

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