Molecular Playground/Glutamate Receptor
From Proteopedia
A CBI Molecule being studied in the University of Massachusetts Amherst Chemistry-Biology Interface Program at UMass Amherst and on display at the Molecular Playground.
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Glutamate Receptor
Full view of the glutamate receptor shows the overall structure (amino-terminal, ligand-binding and transmembrane domains) in both (MF) and models. Banner: The glutamate receptor is found in our brains and allows neurons to talk to each other
Zooming in at the top of the receptor () one can view the amino terminal domain, which is a part of the extracellular domain. This domain is implicated in receptor assembly, trafficking, and localization.
Moving toward the bottom of the receptor () (SM)one can view the transmembrane domain.
This view () highlights the area where a receptor antagonist, 2K200225, will bind.
Close up view of the ligand binding site ()(AH) of the nature ligand glutamate.
Molecular Playground banner: A receptor involved in excitatory neurotransmission. It's so pretty!
Proteopedia Page Contributors and Editors (what is this?)
Devon McCarthy, Rosie Combs-Bachmann, Mariel Feliciano, Steve McCarron, Amanda Hussey, Michal Harel, Jaime Prilusky, Alexander Berchansky, Lynmarie K Thompson, David Canner
