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2xez

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Revision as of 04:32, 7 July 2010 by OCA (Talk | contribs)
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Image:2xez.jpg

Template:STRUCTURE 2xez

CRYSTAL STRUCTURE OF CHECKPOINT KINASE 1 (CHK1) IN COMPLEX WITH INHIBITORS

Template:ABSTRACT PUBMED 20561787

About this Structure

2XEZ is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Matthews TP, McHardy T, Klair S, Boxall K, Fisher M, Cherry M, Allen CE, Addison GJ, Ellard J, Aherne GW, Westwood IM, van Montfort R, Garrett MD, Reader JC, Collins I. Design and evaluation of 3,6-di(hetero)aryl imidazo[1,2-a]pyrazines as inhibitors of checkpoint and other kinases. Bioorg Med Chem Lett. 2010 Jul 15;20(14):4045-9. Epub 2010 May 27. PMID:20561787 doi:10.1016/j.bmcl.2010.05.096
  • Matthews TP, Klair S, Burns S, Boxall K, Cherry M, Fisher M, Westwood IM, Walton MI, McHardy T, Cheung KM, Van Montfort R, Williams D, Aherne GW, Garrett MD, Reader J, Collins I. Identification of inhibitors of checkpoint kinase 1 through template screening. J Med Chem. 2009 Aug 13;52(15):4810-9. PMID:19572549 doi:10.1021/jm900314j

Page seeded by OCA on Wed Jul 7 08:38:44 2010

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