2k4l

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Template:STRUCTURE 2k4l

Solution structure of a 2:1C2-(2-naphthyl)pyrrolo[2,1-c][1,4]benzodiazepine (PBD) DNA adduct: molecular basis for unexpectedly high DNA helix stabilization.

Template:ABSTRACT PUBMED 18925745

About this Structure

2K4L is a Single protein structure. Full experimental information is available from OCA.

Reference

Solution Structure of a 2:1 C2-(2-Naphthyl) Pyrrolo[2,1-c][1,4]benzodiazepine DNA Adduct: Molecular Basis for Unexpectedly High DNA Helix Stabilization., Antonow D, Barata T, Jenkins TC, Parkinson GN, Howard PW, Thurston DE, Zloh M, Biochemistry. 2008 Oct 17. PMID:18925745

Parallel synthesis of a novel C2-aryl pyrrolo[2,1-c][1,4]benzodiazepine (PBD) library., Antonow D, Cooper N, Howard PW, Thurston DE, J Comb Chem. 2007 May-Jun;9(3):437-45. Epub 2007 Mar 31. PMID:17397227

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