3lg4

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Image:3lg4.jpg

Template:STRUCTURE 3lg4

Staphylococcus aureus V31Y, F92I mutant dihydrofolate reductase complexed with NADPH and 5-[(3S)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine

Template:ABSTRACT PUBMED 20643959

About this Structure

3LG4 is a 2 chains structure with sequences from Staphylococcus aureus. Full crystallographic information is available from OCA.

Reference

  • Frey KM, Georgiev I, Donald BR, Anderson AC. Predicting resistance mutations using protein design algorithms. Proc Natl Acad Sci U S A. 2010 Jul 19. PMID:20643959

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