3ksw
From Proteopedia
Crystal structure of sterol 14alpha-demethylase (CYP51) from Trypanosoma cruzi in complex with an inhibitor VNF ((4-(4-chlorophenyl)-N-[2-(1H-imidazol-1-yl)-1-phenylethyl]benzamide)
Template:ABSTRACT PUBMED 20530488
About this Structure
3KSW is a 1 chain structure with sequence from Trypanosoma cruzi. Full crystallographic information is available from OCA.
Reference
- Lepesheva GI, Hargrove TY, Anderson S, Kleshchenko Y, Furtak V, Wawrzak Z, Villalta F, Waterman MR. Structural insights into inhibition of sterol 14alpha-demethylase in the human pathogen Trypanosoma cruzi. J Biol Chem. 2010 Aug 13;285(33):25582-90. Epub 2010 Jun 8. PMID:20530488 doi:10.1074/jbc.M110.133215
Page seeded by OCA on Wed Jun 23 08:35:02 2010
Categories: Sterol 14-demethylase | Trypanosoma cruzi | Anderson, S. | Hargrove, T Y. | Lepesheva, G I. | Waterman, M R. | Wawrzak, Z. | Cyp51 | Cytochrome p450 | Endoplasmic reticulum | Heme | Heme thiolate protein | Iron | Lipid synthesis | Lipid | Membrane | Metal-binding | Monooxygenase | Nadp | Oxidoreductase | Polymorphism | Steroid biosynthesis | Sterol 14-alpha demethylase | Sterol biosynthesis | Transmembrane protein