Calmodulin

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Image:1prw.png
Crystal structure of bovine brain Ca++ calmodulin in a compact form, 1prw

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Calmodulin (CaM) – calcium modulated protein – regulates various protein targets. It is used by various proteins as calcium sensor and signal transducer by binding to their calcium binding domain (CBD). It undergoes conformational change upon binding Ca++ via its 4 EF hand motives and can undergo post-translational modification.

Calmodulin

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Conformational change of Calmodulin

Calmodulin in Motion


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