3f5p

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Template:STRUCTURE 3f5p

Contents 1 Complex Structure of Insulin-like Growth Factor Receptor and 3-Cyanoquinoline Inhibitor 2 Disease 3 About this Structure 4 Reference

Complex Structure of Insulin-like Growth Factor Receptor and 3-Cyanoquinoline Inhibitor

Template:ABSTRACT PUBMED 19041240

Disease

Known disease associated with this structure: Intrauterine and postnatal growth retardation OMIM:[147370]

About this Structure

3F5P is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Lead identification to generate 3-cyanoquinoline inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment., Miller LM, Mayer SC, Berger DM, Boschelli DH, Boschelli F, Di L, Du X, Dutia M, Floyd MB, Johnson M, Kenny CH, Krishnamurthy G, Moy F, Petusky S, Tkach D, Torres N, Wu B, Xu W, Bioorg Med Chem Lett. 2009 Jan 1;19(1):62-6. Epub 2008 Nov 17. PMID:19041240

Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment., Mayer SC, Banker AL, Boschelli F, Di L, Johnson M, Kenny CH, Krishnamurthy G, Kutterer K, Moy F, Petusky S, Ravi M, Tkach D, Tsou HR, Xu W, Bioorg Med Chem Lett. 2008 Jun 15;18(12):3641-5. Epub 2008 Apr 25. PMID:18501599[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]

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