User:Marcin Jozef Suskiewicz/Sandbox Parvin/

From Proteopedia

Alpha-parvin^[1], also known as actopaxin^[2] or CH domain-containing ILK-binding protein (CH-ILK-BP)^[3] is an adapter protein known to interact with a number of focal adhesion proteins leading to focal adhesion stabilisation. It is crucial for essential directional cell migration during embryogenesis in mice^[4]. Dynamic changes in its phosphorylation status at serines 4 and 8 and consequent changes in affinities towards its binding partners may be responsible for focal adhesion turnover (disassembly of old adhesions, assembly of new ones) observed during cell migration.^[5][6][7][8]