2beb

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Image:2beb.png

Template:STRUCTURE 2beb

X-ray structure of Asn to Thr mutant of Winged Bean Chymotrypsin inhibitor

Template:ABSTRACT PUBMED 16734415

About this Structure

2BEB is a 2 chains structure of sequences from Psophocarpus tetragonolobus. Full crystallographic information is available from OCA.

Reference

  • Dasgupta J, Khamrui S, Dattagupta JK, Sen U. Spacer Asn determines the fate of Kunitz (STI) inhibitors, as revealed by structural and biochemical studies on WCI mutants. Biochemistry. 2006 Jun 6;45(22):6783-92. PMID:16734415 doi:10.1021/bi060374q
  • Khamrui S, Dasgupta J, Dattagupta JK, Sen U. Single mutation at P1 of a chymotrypsin inhibitor changes it to a trypsin inhibitor: X-ray structural (2.15 A) and biochemical basis. Biochim Biophys Acta. 2005 Aug 31;1752(1):65-72. PMID:16081330 doi:10.1016/j.bbapap.2005.06.012

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