2pob

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Image:2pob.png

Template:STRUCTURE 2pob

PPARgamma Ligand binding domain complexed with a farglitazar analogue gw4709

Template:ABSTRACT PUBMED 17533125

About this Structure

2POB is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Trump RP, Cobb JE, Shearer BG, Lambert MH, Nolte RT, Willson TM, Buckholz RG, Zhao SM, Leesnitzer LM, Iannone MA, Pearce KH, Billin AN, Hoekstra WJ. Co-crystal structure guided array synthesis of PPARgamma inverse agonists. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3916-20. Epub 2007 May 18. PMID:17533125 doi:10.1016/j.bmcl.2007.04.111

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