2f7d

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Template:STRUCTURE 2f7d

A mutant rabbit cathepsin K with a nitrile inhibitor

Template:ABSTRACT PUBMED 16451072

About this Structure

2F7D is a 1 chain structure of sequence from Oryctolagus cuniculus. Full crystallographic information is available from OCA.

Reference

  • Crane SN, Black WC, Palmer JT, Davis DE, Setti E, Robichaud J, Paquet J, Oballa RM, Bayly CI, McKay DJ, Somoza JR, Chauret N, Seto C, Scheigetz J, Wesolowski G, Masse F, Desmarais S, Ouellet M. Beta-substituted cyclohexanecarboxamide: a nonpeptidic framework for the design of potent inhibitors of cathepsin K. J Med Chem. 2006 Feb 9;49(3):1066-79. PMID:16451072 doi:10.1021/jm051059p

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