1seu
From Proteopedia
Contents |
Human DNA Topoisomerase I (70 Kda) In Complex With The Indolocarbazole SA315F and Covalent Complex With A 22 Base Pair DNA Duplex
Template:ABSTRACT PUBMED 15801827
Disease
Known disease associated with this structure: DNA topoisomerase I, camptothecin-resistant OMIM:[126420]
About this Structure
1SEU is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Staker BL, Feese MD, Cushman M, Pommier Y, Zembower D, Stewart L, Burgin AB. Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex. J Med Chem. 2005 Apr 7;48(7):2336-45. PMID:15801827 doi:10.1021/jm049146p
Page seeded by OCA on Tue Feb 17 21:16:58 2009
Categories: DNA topoisomerase | Homo sapiens | Burgin, A B. | Cushman, M. | Feese, M D. | Pommier, Y. | Staker, B L. | Stewart, L. | Zembower, D. | Dna | Drug | Poison | Topoisomerase i