3gkw

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Image:3gkw.jpg

Template:STRUCTURE 3gkw

Crystal structure of the Fab fragment of Nimotuzumab. An anti-epidermal growth factor receptor antibody

Template:ABSTRACT PUBMED 19584289

About this Structure

3GKW is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Talavera A, Friemann R, Gomez-Puerta S, Martinez-Fleites C, Garrido G, Rabasa A, Lopez-Requena A, Pupo A, Johansen RF, Sanchez O, Krengel U, Moreno E. Nimotuzumab, an antitumor antibody that targets the epidermal growth factor receptor, blocks ligand binding while permitting the active receptor conformation. Cancer Res. 2009 Jul 15;69(14):5851-9. Epub 2009 Jul 7. PMID:19584289 doi:10.1158/0008-5472.CAN-08-4518

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