1qj7

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Image:1qj7.png

Template:STRUCTURE 1qj7

NOVEL COVALENT ACTIVE SITE THROMBIN INHIBITORS

Template:ABSTRACT PUBMED 10387040

About this Structure

1QJ7 is a 3 chains structure of sequences from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Jhoti H, Cleasby A, Reid S, Thomas PJ, Weir M, Wonacott A. Crystal structures of thrombin complexed to a novel series of synthetic inhibitors containing a 5,5-trans-lactone template. Biochemistry. 1999 Jun 22;38(25):7969-77. PMID:10387040 doi:http://dx.doi.org/10.1021/bi9830359

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