2fxm

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Image:2fxm.png

Template:STRUCTURE 2fxm

Structure of the human beta-myosin S2 fragment

Template:ABSTRACT PUBMED 17095604

About this Structure

2FXM is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Blankenfeldt W, Thoma NH, Wray JS, Gautel M, Schlichting I. Crystal structures of human cardiac beta-myosin II S2-Delta provide insight into the functional role of the S2 subfragment. Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17713-7. Epub 2006 Nov 9. PMID:17095604
  • Gruen M, Gautel M. Mutations in beta-myosin S2 that cause familial hypertrophic cardiomyopathy (FHC) abolish the interaction with the regulatory domain of myosin-binding protein-C. J Mol Biol. 1999 Feb 26;286(3):933-49. PMID:10024460 doi:http://dx.doi.org/10.1006/jmbi.1998.2522
  • Li Y, Brown JH, Reshetnikova L, Blazsek A, Farkas L, Nyitray L, Cohen C. Visualization of an unstable coiled coil from the scallop myosin rod. Nature. 2003 Jul 17;424(6946):341-5. PMID:12867988 doi:http://dx.doi.org/10.1038/nature01801

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