3gqf

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Template:STRUCTURE 3gqf

Contents

Structural and Biophysical Properties of the Pathogenic SOD1 Variant H46R/H48Q

Template:ABSTRACT PUBMED 19227972

Disease

Known disease associated with this structure: Amyotrophic lateral sclerosis, due to SOD1 deficiency OMIM:[147450]

About this Structure

3GQF is a 6 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Winkler DD, Schuermann JP, Cao X, Holloway SP, Borchelt DR, Carroll MC, Proescher JB, Culotta VC, Hart PJ. Structural and biophysical properties of the pathogenic SOD1 variant H46R/H48Q. Biochemistry. 2009 Apr 21;48(15):3436-47. PMID:19227972 doi:10.1021/bi8021735

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