1tjt

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Image:1tjt.png

Template:STRUCTURE 1tjt

Contents

X-ray structure of the human alpha-actinin isoform 3 at 2.2A resolution

Template:ABSTRACT PUBMED 15808860

Disease

Known disease associated with this structure: Alpha-actinin-3 deficiency OMIM:[102574], Sprinting performance OMIM:[102574]

About this Structure

1TJT is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Franzot G, Sjoblom B, Gautel M, Djinovic Carugo K. The crystal structure of the actin binding domain from alpha-actinin in its closed conformation: structural insight into phospholipid regulation of alpha-actinin. J Mol Biol. 2005 Apr 22;348(1):151-65. PMID:15808860 doi:http://dx.doi.org/10.1016/j.jmb.2005.01.002

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