2hfp

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Image:2hfp.png

Template:STRUCTURE 2hfp

Crystal Structure of PPAR Gamma with N-sulfonyl-2-indole carboxamide ligands

Template:ABSTRACT PUBMED 16919947

About this Structure

2HFP is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hopkins CR, O'neil SV, Laufersweiler MC, Wang Y, Pokross M, Mekel M, Evdokimov A, Walter R, Kontoyianni M, Petrey ME, Sabatakos G, Roesgen JT, Richardson E, Demuth TP Jr. Design and synthesis of novel N-sulfonyl-2-indole carboxamides as potent PPAR-gamma binding agents with potential application to the treatment of osteoporosis. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5659-63. Epub 2006 Aug 21. PMID:16919947 doi:http://dx.doi.org/10.1016/j.bmcl.2006.08.003

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