2jiu
From Proteopedia
CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN T790M MUTATION IN COMPLEX WITH AEE788
Template:ABSTRACT PUBMED 18227510
About this Structure
2JIU is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Yun CH, Mengwasser KE, Toms AV, Woo MS, Greulich H, Wong KK, Meyerson M, Eck MJ. The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2070-5. Epub 2008 Jan 28. PMID:18227510
Page seeded by OCA on Sun Mar 22 10:31:35 2009
Categories: Homo sapiens | Transferase | Eck, M J. | Greulich, H. | Mengwasser, K E. | Meyerson, M. | Toms, A V. | Wong, K K. | Woo, M S. | Yun, C H. | Aee788 | Alternative splicing | Anti-oncogene | Atp-binding | Cell cycle | Disease mutation | Egfr | Epidermal growth factor | Kinase | Nucleotide-binding | Phosphorylation | Receptor | T790m | Transmembrane | Tyrosine-protein kinase
