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2r2m
From Proteopedia
Contents |
2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors
Template:ABSTRACT PUBMED 17889527
About this Structure
2r2m is a 3 chain structure of Hirudin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Lee L, Kreutter KD, Pan W, Crysler C, Spurlino J, Player MR, Tomczuk B, Lu T. 2-(2-Chloro-6-fluorophenyl)acetamides as potent thrombin inhibitors. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6266-9. Epub 2007 Sep 8. PMID:17889527 doi:10.1016/j.bmcl.2007.09.013
Categories: Hirudo medicinalis | Homo sapiens | Thrombin | Spurlino, J. | Acute phase | Blood coagulation | Calcium | Cleavage on pair of basic residue | Disease mutation | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Kringle | Polymorphism | Protease | Protease inhibitor | Secreted | Serine protease | Serine protease inhibitor | Sulfation | Zymogen
