Ribosomal protein S16

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Image:RPS16.png
Crystal Structure of Ribosomal protein S16 from 2zm6, chain P

Template:STRUCTURE 2zm6

Ribosomal protein S16 (RPS16) is one of the 22 proteins which belong to the of the bacterial ribosome. It exhibits endonuclease activity. The images at the left and at the right correspond to one representative RPS16, i.e. the crystal structure of Ribosomal protein S16 from Thermus thermophilus (2zm6, chain P).




3D Structures of Ribosomal protein S16

S16

3bn0 – RPS16 – Aquifex aeolicus
1emw – TtRPS16 – NMR - Thermus thermophilus

S16 in small ribosomal subunit

2zm6, 1n36, 1j5e, 3oge, 3ogy, 3ohc, 3ohd, 3ohy, 3oi0, 3oi2, 3oi4, 3oto - TtRPS5 in 30S ribosomal subunit+THX+16S RRNA – Thermus thermophilus
2vqe, 2vqf, 2uuc, 2e5l, 2uu9, 2uua, 2uub - TtRPS5 in 30S ribosomal subunit+16S RRNA+RNA fragment
3kc4 – EcRPS5 in 30S ribosomal subunit - Escherichia coli
3i1m, 3i1o, 3df1, 3df3, 2vho, 2vhp, 2avy, 2aw7, 1pnx, 3oaq, 3oar, 3ofa, 3ofb, 3ofo, 3ofp, 3ofx, 3ofy, 3or9, 3ora - EcRPS5 in 30S ribosomal subunit+16S RRNA
1i94, 1fka - TtRPS5 in 30S ribosomal subunit+16S RRNA
1p87, 1p6g - EcRPS5 in 30S ribosomal subunit+16S RRNA – Cryo-EM
3bbn - RPS5 in 30S ribosomal subunit+16S RRNA – Cryo-EM – spinach

S16 in small + large ribosomal subunit

1ml5 - EcRPS5 in 30S ribosomal subunit+50S ribosomal subunit+THX+chain release factor 2+P-site tRNA+tRNA Phe+mRNA fragment+23S RRNA+5S RRNA+16S RRNA - EM

S16 in small ribosomal subunit+ chain release factor

3mr8, 3ms0 – TtRPS5 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+mRNA+16S RRNA
3d5a, 3d5c - TtRPS5 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+E-site tRNA+mRNA +16S RRNA
2b64 - TtRPS5 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 1
2b9m - TtRPS5 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 2
2x9r, 2x9t, 2wh1, 2wh3 - TtRPS5 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+mRNA +16S RRNA
3f1e, 3f1g - TtRPS5 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+E-site tRNA +16S RRNA

S16 in small ribosomal subunit+tRNA+mRNA

2hgi - TtRPS5 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet
2hgp - TtRPS5 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA
2i2p, 2i2u - EcRPS5 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA
2hgr - TtRPS5 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet+mRNA
1yl4 – TtRPS5 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+THRS mRNA operator
1pns - EcRPS5 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+mRNA
1xnq, 1xnr - TtRPS5 in 30S ribosomal subunit+THX+mRNA+tRNA anticodon+16S RRNA

S16 in small ribosomal subunit+A-site tRNA

2uxd, 2uxc - TtRPS5 in 30S ribosomal subunit+THX+A-site mRNA CGGG+tRNA anticodon+16S RRNA
1n32, 1n33 - TtRPS5 in 30S ribosomal subunit+THX+A-site mRNA fragment+tRNA anticodon+16S RRNA
1n34 - TtRPS5 in 30S ribosomal subunit+THX+A-site mRNA fragment +16S RRNA
1xmo, 1xmq - TtRPS5 in 30S ribosomal subunit+THX+A-site mRNA+tRNA anticodon+16S RRNA
2uxb - TtRPS5 in 30S ribosomal subunit+THX+A-site mRNA GGGU+tRNA anticodon+16S RRNA

S16 in small ribosomal subunit+P-site tRNA

3i8g - TtRPS5 in 30S ribosomal subunit+P-site tRNA+mRNA +16S RRNA
3i8h, 3i9b, 3i9d - TtRPS5 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA
1ibk - TtRPS5 in 30S ribosomal subunit+THX+P-site mRNA fragment +16S RRNA
2wwl - EcRPS5 in 30S ribosomal subunit+Poly-Ala chain+P-site tRNA+mRNA +16S RRNA - Escherichia coli
3i1q - EcRPS5 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA
3i1s, 3i1z, 3i21 - EcRPS5 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA +16S RNA

S16 in small ribosomal subunit+A-site tRNA+P-site tRNA

1ibl, 1ibm - TtRPS5 in 30S ribosomal subunit+THX+A-site mRNA fragment+P-site mRNA fragment+tRNA anticodon+16S RRNA

S16 in small ribosomal subunit+P-site tRNA+E-site tRNA

2ow8 - TtRPS5 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA+mRNA +16S RRNA
2b9o - TtRPS5 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA
2qnh - TtRPS5 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA

S16 in small ribosomal subunit+A-site tRNA+P-site tRNA+E-site tRNA

2gy9, 2gyb - EcRPS5 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA – Cryo-EM
1jgo, 1jgp, 1jgq, 1gix - TtRPS5 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+tRNA Phe+mRNA +16S RRNA
3e1a, 3e1c - EcRPS5 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA

S16 in small ribosomal subunit + antibiotics

1i95 - TtRPS5 in 30S ribosomal subunit+16S RRNA+edeine
1i97 - TtRPS5 in 30S ribosomal subunit+16S RRNA+tetracycline
1hnw - TtRPS5 in 30S ribosomal subunit+16S RRNA+mRNA fragment+tetracycline
1hnx - TtRPS5 in 30S ribosomal subunit+16S RRNA+mRNA fragment+pactamycin
1hnz - TtRPS5 in 30S ribosomal subunit+16S RRNA+mRNA fragment+hygromycin B
1fjg - TtRPS5 in 30S ribosomal subunit+16S RRNA+mRNA fragment+streptomycin
2qbb, 2qb9 - EcRPS5 in 30S ribosomal subunit+16S RRNA+kasugamyin
2hhh - TtRPS5 in 30S ribosomal subunit+16S RRNA+kasugamyin
2f4v - TtRPS5 in 30S ribosomal subunit+16S RRNA+designed antibiotic
1vs5, 1vs7 - EcRPS5 in 30S ribosomal subunit+16S RRNA+gentamicin
2qan, 2qal - EcRPS5 in 30S ribosomal subunit+16S RRNA+neomycin
2qou, 2qow - EcRPS5 in 30S ribosomal subunit+16S RRNA+spectinomycin
2qoy, 2qp0 - EcRPS5 in 30S ribosomal subunit+16S RRNA+spectinomycin+neomycin
2z4k, 2z4m - EcRPS5 in 30S ribosomal subunit+16S RRNA+paromomycin
2j00, 2j02 - TtRPS5 in 30S ribosomal subunit+16S RRNA+paromomycin+P-site tRNA fMet+E-site tRNA Phe+mRNA
2wdg, 2wdh, 2wdk, 2wdm - TtRPS14 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA+tRNA Phe+paromomycin
3knj, 3knh - TtRPS5 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+viomycin
3knl, 3knn - TtRPS5 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+capreomycin

S16 in small ribosomal subunit + ribosome recycling factor

2qbd, 2qbf - EcRPS5 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor
2qbh, 2qbj - EcRPS5 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+gentamicin
2v46, 2v48 - TtRPS5 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+P-site tRNA Phe+mRNA+tRNA fMet


S16 in small ribosomal subunit + elongation factor

2wri, 2wrk, 2xsy, 2xuy - TtRPS5 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA+elongation factor G
2wrn, 2wrq - TtRPS5 in 30S ribosomal subunit+THX+A-site tRNA+mRNA +16S RRNA+elongation factor TU-4
3fic - TtRPS5 in 30S ribosomal subunit+THX+A-site tRNA+P-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU-A
2xqd – TtRPS16 in 30S ribosomal subunit+THX+E-site tRNA+mRNA +16S RRNA+elongation factor TU-B
3fih - EcRPS5 in 30S ribosomal subunit+A-site tRNA Phe+P-site tRNA+mRNA +16S RRNA+elongation factor TU
3huw, 3huy - TtRPS5 in 30S ribosomal subunit+THX+tRNA-Met+mRNA +16S RRNA+elongation factor P
1s1h - yRPS16 in 40S ribosomal subunit+18S RRNA+elongation factor 2 – Cryo-EM – yeast

S16 in small ribosomal subunit + translation initiation factor

1i96 - TtRPS5 in 30S ribosomal subunit+THX+IF3+16S RRNA
1hr0 - TtRPS5 in 30S ribosomal subunit+THX+IF+16S RRNA

S16 in small ribosomal subunit + various proteins

3kiq, 3kis, 3kiu, 3kix - TtRPS5 in 30S ribosomal subunit+toxin RelE+16S RRNA
1voq, 1vos, 1vov, 1vox, 1voz - EcRPS5 in 30S ribosomal subunit+protein Y+16S RRNA
2xfz, 2xg1 - TtRPS14 in 30S ribosomal subunit+tRNA Phe+mRNA+colicin E3+16S RRNA
3jyv - RPS14+RPS0+RPS2+RPS3+RPS5+RPS9+RPS11+RPS13+RPS15+RPS16+RPS18+RPS20+RPS22+RPS23+RPS29+18S RRNA+RACK1+S19E+tRNA – Cryo-EM - Thermomyces lanuginosus
2zkq – RPS16 in 40S ribosomal subunit+RNA fragments+RACK1+18S RRNA
3iz6 – RPS16 in 40S ribosomal subunit+RACK1 – wheat – Cryo EM
3o2z, 3o30 – yRPS16 in 40S ribosomal subunit+18S RRNA+RACK1

S16 in part of small ribosomal subunit

3iy8 – EcRPS16+EcRPS5+EcRPS6+EcRPS8+EcRPS9+ EcRPS11+EcRPS12+EcRPS15+EcRPS17+EcRPS18+Leishmania taretolae mRNA

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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