ExbB

From Proteopedia

ExbB is essential for TonB-dependent energy transduction as the absence of ExbB prevents TonB responding to the proton motive force, as well as the change of the high-affinity association of TonB for the outer membrane to the cytoplasmic membrane. ^[1]

ExbB can exist in the TonB system either in a complex with ExbD (to a ratio of 3.5:1) or on its own (where no ExbD is present), which has been suggested to play a role in the diverse roles of TonB. ^[1]

Structure

The Structure of ExbB

ExbB consists of three transmembrane domains, with two large portions of the protein representing the majority of the protein in the cytoplasm and two smaller portions in the periplasm.

References

1. ↑ ^{1.0 1.1} Held KG, Postle K. ExbB and ExbD do not function independently in TonB-dependent energy transduction. J Bacteriol. 2002 Sep;184(18):5170-3. PMID:12193634