Colicin E2
From Proteopedia
Colicin E2 is a type of Colicin, a bacteriocin made by E. coli which acts against other nearby E. coli to kill them with its DNase activity; it digests the host genome, leading to its death.
Synthesis and release
The ColE2 operon is encoded on a plasmid in E. coli, alongside its Colicin Immunity Protein, Imm. This protects the colicinogenic cell from the cytotoxic activity of the colicin.
Mechanism of uptake
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| 2ysu, resolution 3.50Å () | |||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Colicin E2 binds to the BtuB receptor on the target E. coli cell to begin its translocation across the membrane. This structure shows the binding between (blue) and the (green).
