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Please do NOT make changes to this Sandbox until after May 10, 2011. Sandbox 100 is reserved until then for use by John Ripollone - Messiah College, Grantham, PA (under the supervision of Dr. Hannah Tims).

spinqualitylabelsall models Molecular Structure of Ciprofloxacin Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Ciprofloxacin

Page under construction - by: John Ripollone, Department of Biological Sciences (in conjunction with the Department of Chemistry and Biochemistry) - Messiah College, Grantham, PA 17027.

General Information

Ciprofloxacin is a broad-spectrum fluoroquinone antibiotic that is generally effective against both aerobic gram-positive and aerobic gram-negative bacteria. Bacterial organisms that have been shown to be targeted by ciprofloxacin are:

Aerobic Gram-Positive Bacteria (With Certain Strain Particularities): Enterococcus faecalis, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus saprophyticus, Streptococcus pneumoniae, etc.

Aerobic Gram-Negative Bacteria (With Certain Strain Particularities): Campylobacter jejuni, Citrobacter freundii, Enterobacter cloacae, Escherichia coli, Haemophilus influenzae, etc.

Structure

Ciprofloxacin is a 1-cyclopropyl-6-floro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid with molecular formula: C₁₇H₁₈FN₃O₃.

spinqualitylabelsall models AcrB Multidrug Efflux Pump with Attached Ciprofloxacin Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

spinqualitylabelsall models Twinned Structure of S. Aureus Gyrase Complex with Attached Ciprofloxacin and DNA Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image