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Aldose Reductase (2IKH)
Wikipedia
Introduction
Aldose reductase is an oxidoreductase/dehydrogenase enzyme.[1]
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In summary, this study provides the platform for further structure-guided design hypotheses of novel drug candidates with higher affinity and selectivity.[2]
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References
- ↑ Wikipedia. Aldose Reductase. http://en.wikipedia.org/wiki/Aldose_reductase
- ↑ Steuber H, Heine A, Klebe G. Structural and thermodynamic study on aldose reductase: nitro-substituted inhibitors with strong enthalpic binding contribution. J Mol Biol. 2007 May 4;368(3):618-38. Epub 2006 Dec 15. PMID:17368668 doi:10.1016/j.jmb.2006.12.004