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3bcm

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Image:3bcm.png

Template:STRUCTURE 3bcm

Crystal Structure of The Unswapped Form of P19A/L28Q/N67D BS-RNase

Template:ABSTRACT PUBMED 18164315

About this Structure

3BCM is a 2 chains structure with sequences from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Merlino A, Ercole C, Picone D, Pizzo E, Mazzarella L, Sica F. The buried diversity of bovine seminal ribonuclease: shape and cytotoxicity of the swapped non-covalent form of the enzyme. J Mol Biol. 2008 Feb 15;376(2):427-37. Epub 2007 Nov 12. PMID:18164315 doi:http://dx.doi.org/10.1016/j.jmb.2007.11.008
  • Sica F, Di Fiore A, Merlino A, Mazzarella L. Structure and stability of the non-covalent swapped dimer of bovine seminal ribonuclease: an enzyme tailored to evade ribonuclease protein inhibitor. J Biol Chem. 2004 Aug 27;279(35):36753-60. Epub 2004 Jun 9. PMID:15192098 doi:http://dx.doi.org/10.1074/jbc.M405655200
  • Mazzarella L, Capasso S, Demasi D, Di Lorenzo G, Mattia CA, Zagari A. Bovine seminal ribonuclease: structure at 1.9 A resolution. Acta Crystallogr D Biol Crystallogr. 1993 Jul 1;49(Pt 4):389-402. PMID:15299514 doi:http://dx.doi.org/10.1107/S0907444993003403
  • Merlino A, Vitagliano L, Sica F, Zagari A, Mazzarella L. Population shift vs induced fit: the case of bovine seminal ribonuclease swapping dimer. Biopolymers. 2004 Apr 15;73(6):689-95. PMID:15048772 doi:http://dx.doi.org/10.1002/bip.20016
  • Sica F, Di Fiore A, Zagari A, Mazzarella L. The unswapped chain of bovine seminal ribonuclease: Crystal structure of the free and liganded monomeric derivative. Proteins. 2003 Aug 1;52(2):263-71. PMID:12833549 doi:http://dx.doi.org/10.1002/prot.10407
  • Vitagliano L, Adinolfi S, Sica F, Merlino A, Zagari A, Mazzarella L. A potential allosteric subsite generated by domain swapping in bovine seminal ribonuclease. J Mol Biol. 1999 Oct 29;293(3):569-77. PMID:10543951 doi:http://dx.doi.org/10.1006/jmbi.1999.3158
  • Vitagliano L, Adinolfi S, Riccio A, Sica F, Zagari A, Mazzarella L. Binding of a substrate analog to a domain swapping protein: X-ray structure of the complex of bovine seminal ribonuclease with uridylyl(2',5')adenosine. Protein Sci. 1998 Aug;7(8):1691-9. PMID:10082366 doi:http://dx.doi.org/10.1002/pro.5560070804

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