This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2io6

From Proteopedia

Revision as of 05:57, 18 February 2009 by OCA (Talk | contribs)
Jump to: navigation, search
Image:2io6.png

Template:STRUCTURE 2io6

Wee1 kinase complexed with inhibitor PD330961

Template:ABSTRACT PUBMED 17869387

About this Structure

2IO6 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Smaill JB, Baker EN, Booth RJ, Bridges AJ, Dickson JM, Dobrusin EM, Ivanovic I, Kraker AJ, Lee HH, Lunney EA, Ortwine DF, Palmer BD, Quin J 3rd, Squire CJ, Thompson AM, Denny WA. Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases. Eur J Med Chem. 2008 Jun;43(6):1276-96. Epub 2007 Aug 6. PMID:17869387 doi:10.1016/j.ejmech.2007.07.016
  • Squire CJ, Dickson JM, Ivanovic I, Baker EN. Structure and inhibition of the human cell cycle checkpoint kinase, Wee1A kinase: an atypical tyrosine kinase with a key role in CDK1 regulation. Structure. 2005 Apr;13(4):541-50. PMID:15837193 doi:10.1016/j.str.2004.12.017

Page seeded by OCA on Wed Feb 18 07:57:05 2009

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2io6"
Personal tools