1sn6

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Image:1sn6.png

Template:STRUCTURE 1sn6

Contents

NMR solution structure of human Saposin C in SDS micelles

Template:ABSTRACT PUBMED 15713488

Disease

Known disease associated with this structure: Combined SAP deficiency OMIM:[176801], Gaucher disease, atypical OMIM:[176801], Krabbe disease, atypical OMIM:[176801], Metachromatic leukodystrophy due to SAP-b deficiency OMIM:[176801]

About this Structure

1SN6 is a 1 chain structure of sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Hawkins CA, de Alba E, Tjandra N. Solution structure of human saposin C in a detergent environment. J Mol Biol. 2005 Mar 11;346(5):1381-92. Epub 2005 Jan 20. PMID:15713488 doi:10.1016/j.jmb.2004.12.045
  • de Alba E, Weiler S, Tjandra N. Solution structure of human saposin C: pH-dependent interaction with phospholipid vesicles. Biochemistry. 2003 Dec 23;42(50):14729-40. PMID:14674747 doi:10.1021/bi0301338

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