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1qlp

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Image:1qlp.png

Template:STRUCTURE 1qlp

2.0 ANGSTROM STRUCTURE OF INTACT ALPHA-1-ANTITRYPSIN: A CANONICAL TEMPLATE FOR ACTIVE SERPINS

Template:ABSTRACT PUBMED 10933492

About this Structure

1qlp is a 1 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2psi. Full crystallographic information is available from OCA.

Reference

  • Elliott PR, Pei XY, Dafforn TR, Lomas DA. Topography of a 2.0 A structure of alpha1-antitrypsin reveals targets for rational drug design to prevent conformational disease. Protein Sci. 2000 Jul;9(7):1274-81. PMID:10933492
  • Elliott PR, Abrahams JP, Lomas DA. Wild-type alpha 1-antitrypsin is in the canonical inhibitory conformation. J Mol Biol. 1998 Jan 23;275(3):419-25. PMID:9466920 doi:S0022-2836(97)91458-3

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OCA

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