2j4g

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Image:2j4g.png

Template:STRUCTURE 2j4g

BACTEROIDES THETAIOTAOMICRON GH84 O-GLCNACASE IN COMPLEX WITH N-BUTYL-THIAZOLINE INHIBITOR

Template:ABSTRACT PUBMED 17227027

About this Structure

2J4G is a 2 chains structure of sequences from Bacteroides thetaiotaomicron. Full crystallographic information is available from OCA.

Reference

  • Whitworth GE, Macauley MS, Stubbs KA, Dennis RJ, Taylor EJ, Davies GJ, Greig IR, Vocadlo DJ. Analysis of PUGNAc and NAG-thiazoline as transition state analogues for human O-GlcNAcase: mechanistic and structural insights into inhibitor selectivity and transition state poise. J Am Chem Soc. 2007 Jan 24;129(3):635-44. PMID:17227027 doi:http://dx.doi.org/10.1021/ja065697o

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