2kle

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Image:2kle.png

Template:STRUCTURE 2kle

Contents

ISIC Refined Solution Structure of the Calcium Binding Domain of the C-terminal Cytosolic Domain of Polycystin-2

Template:ABSTRACT PUBMED 19636966

Disease

Known disease associated with this structure: Polycystic kidney disease, adult, type II OMIM:[173910]

About this Structure

2KLE is a 1 chain structure of sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Schumann FH, Hoffmeister H, Schmidt M, Bader R, Besl E, Witzgall R, Kalbitzer HR. NMR-assignments of a cytosolic domain of the C-terminus of polycystin-2. Biomol NMR Assign. 2009 Jun;3(1):141-4. Epub 2009 Apr 10. PMID:19636966 doi:10.1007/s12104-009-9160-x
  • Schumann F, Hoffmeister H, Bader R, Schmidt M, Witzgall R, Kalbitzer HR. Ca2+-dependent conformational changes in a C-terminal cytosolic domain of polycystin-2. J Biol Chem. 2009 Sep 4;284(36):24372-83. Epub 2009 Jun 22. PMID:19546223 doi:10.1074/jbc.M109.025635

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