1y2m

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Image:1y2m.png

Template:STRUCTURE 1y2m

Crystal structure of phenylalanine ammonia-lyase from yeast Rhododporidium toruloides

Template:ABSTRACT PUBMED 16006165

About this Structure

1Y2M is a 4 chains structure of sequences from Rhodosporidium toruloides. Full crystallographic information is available from OCA.

Reference

  • Wang L, Gamez A, Sarkissian CN, Straub M, Patch MG, Han GW, Striepeke S, Fitzpatrick P, Scriver CR, Stevens RC. Structure-based chemical modification strategy for enzyme replacement treatment of phenylketonuria. Mol Genet Metab. 2005 Sep-Oct;86(1-2):134-40. Epub 2005 Jul 11. PMID:16006165 doi:10.1016/j.ymgme.2005.05.012
  • Sarkissian CN, Shao Z, Blain F, Peevers R, Su H, Heft R, Chang TM, Scriver CR. A different approach to treatment of phenylketonuria: phenylalanine degradation with recombinant phenylalanine ammonia lyase. Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2339-44. PMID:10051643

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