2qo1
From Proteopedia
2.6 Angstrom Crystal Structure of the Complex Between 11-(decyldithiocarbonyloxy)-undecanoic acid and Mycobacterium Tuberculosis FabH.
Template:ABSTRACT PUBMED 18420147
About this Structure
2QO1 is a 2 chains structure of sequences from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
Reference
- Sachdeva S, Musayev FN, Alhamadsheh MM, Scarsdale JN, Wright HT, Reynolds KA. Separate entrance and exit portals for ligand traffic in Mycobacterium tuberculosis FabH. Chem Biol. 2008 Apr;15(4):402-12. PMID:18420147 doi:10.1016/j.chembiol.2008.03.007
- Scarsdale JN, Kazanina G, He X, Reynolds KA, Wright HT. Crystal structure of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III. J Biol Chem. 2001 Jun 8;276(23):20516-22. Epub 2001 Mar 8. PMID:11278743 doi:10.1074/jbc.M010762200
- Musayev F, Sachdeva S, Scarsdale JN, Reynolds KA, Wright HT. Crystal structure of a substrate complex of Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III (FabH) with lauroyl-coenzyme A. J Mol Biol. 2005 Mar 11;346(5):1313-21. Epub 2005 Jan 20. PMID:15713483 doi:10.1016/j.jmb.2004.12.044
Page seeded by OCA on Mon Feb 16 15:04:03 2009
Categories: Beta-ketoacyl-acyl-carrier-protein synthase I | Mycobacterium tuberculosis | Alhamadsheh, M. | Musayev, F. | Reynolds, K A. | Sachdeva, S. | Scarsdale, J N. | Wright, H T. | Acyltransferase | Cytoplasm | Enzyme inhibitor complex | Fatty acid biosynthesis | Lipid synthesis | Mechanism based inhibitor | Multifunctional enzyme | Myobacterium tuberculosis | Structural basis for substrate specificity | Substrate entry and exit | Transferase