3inl

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Image:3inl.png

Template:STRUCTURE 3inl

Human Mitochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, complexed with agonist Alda-1

Template:ABSTRACT PUBMED 20062057

About this Structure

3INL is a 8 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Perez-Miller S, Younus H, Vanam R, Chen CH, Mochly-Rosen D, Hurley TD. Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant. Nat Struct Mol Biol. 2010 Feb;17(2):159-64. Epub 2010 Jan 10. PMID:20062057 doi:10.1038/nsmb.1737
  • Chen CH, Budas GR, Churchill EN, Disatnik MH, Hurley TD, Mochly-Rosen D. Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart. Science. 2008 Sep 12;321(5895):1493-5. PMID:18787169 doi:321/5895/1493

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