2w5u

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Image:2w5u.jpg

Template:STRUCTURE 2w5u

FLAVODOXIN FROM HELICOBACTER PYLORI IN COMPLEX WITH THE C3 INHIBITOR

Template:ABSTRACT PUBMED 19725577

About this Structure

2W5U is a 2 chains structure of sequences from Helicobacter pylori. Full crystallographic information is available from OCA.

Reference

  • Cremades N, Velazquez-Campoy A, Martinez-Julvez M, Neira JL, Perez-Dorado I, Hermoso J, Jimenez P, Lanas A, Hoffman PS, Sancho J. Discovery of specific flavodoxin inhibitors as potential therapeutic agents against Helicobacter pylori infection. ACS Chem Biol. 2009 Nov 20;4(11):928-38. PMID:19725577 doi:10.1021/cb900166q
  • Martinez-Julvez M, Cremades N, Bueno M, Perez-Dorado I, Maya C, Cuesta-Lopez S, Prada D, Falo F, Hermoso JA, Sancho J. Common conformational changes in flavodoxins induced by FMN and anion binding: the structure of Helicobacter pylori apoflavodoxin. Proteins. 2007 Nov 15;69(3):581-94. PMID:17623845 doi:10.1002/prot.21410
  • Cremades N, Bueno M, Toja M, Sancho J. Towards a new therapeutic target: Helicobacter pylori flavodoxin. Biophys Chem. 2005 Apr 1;115(2-3):267-76. Epub 2005 Jan 7. PMID:15752617 doi:10.1016/j.bpc.2004.12.045

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