Sandbox7 Eric Martz

From Proteopedia

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Proposed Title: Nitrotyrosine.

This page is reserved for a collaboration between User:Eric Martz and Hermes J Garbán.

Nitrotyrosine results from the post-translational modification of the standard amino acid tyrosine. Reactive nitrogen compounds produced in inflammation are typically responsible. Nitrosylation of tyrosine tends to inactivate enzymes. In March, 2011, there are 13 entries in the PDB containing coordinates for 3-nitrotyrosine (meta-nitro-tyrosine), with the compound ID NIY. These include five sequence-distinct proteins, represented by ribonucleotide reductase 2xap, laccase 3div, Human Manganese Superoxide Dismutase 2adp, Human Glutathione Reductase 1k4q, and bovine Cu,Zn superoxide dismutase 1sda.

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See Also

• Nitrotyrosine in Wikipedia.