Sandbox Reserved 196

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This Sandbox is Reserved from Feb 02, 2011, through Jul 31, 2011 for use by the Biochemistry II class at the Butler University at Indianapolis, IN USA taught by R. Jeremy Johnson. This reservation includes Sandbox Reserved 191 through Sandbox Reserved 200.

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Ribonuclease B (RNase B)

Ribonuclease B is structurally the same as RNase A. It has an additional catalytic activity: it can hydrolyze double-stranded RNA at ionic strengths where RNase A has no activity. Outline Intro/Background

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Biology of RNase B

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Description

References

^[1]

1. ↑ Williams RL, Greene SM, McPherson A. The crystal structure of ribonuclease B at 2.5-A resolution. J Biol Chem. 1987 Nov 25;262(33):16020-31. PMID:3680242

spinqualitylabelsall models Ribonuclease B with a strand of DNA in active site Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Additional Resources

• Dr. Johnson