3lgp

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Image:3lgp.png

Template:STRUCTURE 3lgp

Crystal structure of catalytic domain of tace with benzimidazolyl-thienyl-tartrate based inhibitor

Template:ABSTRACT PUBMED 20638281

About this Structure

3LGP is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Li D, Popovici-Muller J, Belanger DB, Caldwell J, Dai C, David M, Girijavallabhan VM, Lavey BJ, Lee JF, Liu Z, Mazzola R, Rizvi R, Rosner KE, Shankar B, Spitler J, Ting PC, Vaccaro H, Yu W, Zhou G, Zhu Z, Niu X, Sun J, Guo Z, Orth P, Chen S, Kozlowski JA, Lundell DJ, Madison V, McKittrick B, Piwinski JJ, Shih NY, Shipps GW Jr, Siddiqui MA, Strickland CO. Structure and activity relationships of tartrate-based TACE inhibitors. Bioorg Med Chem Lett. 2010 Aug 15;20(16):4812-5. Epub 2010 Jun 25. PMID:20638281 doi:10.1016/j.bmcl.2010.06.104

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