Sandbox11

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This sandbox is in use until August 1, 2011 for UMass Chemistry 423. Others please do not edit this page. Thanks!

Chem423 Team Projects: Understanding Drug Mechanisms

Andy Kim, Zach Brentzel, Tyler Vlass, Zach Hitzig

Topic: Acetylcholinesterase bound by Tacrine

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spinqualitylabelsall models PDB ID 1acj Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
1acj, resolution 2.80Å ()
Ligands:
Activity:	Acetylcholinesterase, with EC number 3.1.1.7
Structural annotation: Resources: CATH : 1Acj000 InterPro : Ipr002018, Ipr000908, Ipr000997 Pfam : PF00135 SCOP : d1acj__ UniProt : P04058
Functional annotation: Cellular component: cell junction membrane synapse Biological process: neurotransmitter catabolic process acetylcholine catabolic process in synaptic cleft Molecular function: GPI anchor binding cholinesterase activity acetylcholinesterase activity hydrolase activity
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

Andy Kim, Zach Brentzel, Tyler Vlass, Zach Hitzig-Acetylcholinesterase