3q96
From Proteopedia
B-Raf kinase domain in complex with a tetrahydronaphthalene inhibitor
Template:ABSTRACT PUBMED 21341678
About this Structure
3q96 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Gould AE, Adams R, Adhikari S, Aertgeerts K, Afroze R, Blackburn C, Calderwood EF, Chau R, Chouitar J, Duffey MO, England DB, Farrer C, Forsyth N, Garcia K, Gaulin J, Greenspan PD, Guo R, Harrison SJ, Huang SC, Iartchouk N, Janowick D, Kim MS, Kulkarni B, Langston SP, Liu JX, Ma LT, Menon S, Mizutani H, Paske E, Renou CC, Rezaei M, Rowland RS, Sintchak MD, Smith MD, Stroud SG, Tregay M, Tian Y, Veiby OP, Vos TJ, Vyskocil S, Williams J, Xu T, Yang JJ, Yano J, Zeng H, Zhang DM, Zhang Q, Galvin KM. Design and optimization of potent and orally bioavailable tetrahydronaphthalene raf inhibitors. J Med Chem. 2011 Mar 24;54(6):1836-46. Epub 2011 Feb 22. PMID:21341678 doi:10.1021/jm101479y
