3ert

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Image:3ert.png

Template:STRUCTURE 3ert

HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH 4-HYDROXYTAMOXIFEN

Template:ABSTRACT PUBMED 9875847

About this Structure

3ERT is a 1 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2ert. The September 2003 RCSB PDB Molecule of the Month feature on Estrogen Receptor by David S. Goodsell is 10.2210/rcsb_pdb/mom_2003_9. Full crystallographic information is available from OCA.

Reference

  • Shiau AK, Barstad D, Loria PM, Cheng L, Kushner PJ, Agard DA, Greene GL. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell. 1998 Dec 23;95(7):927-37. PMID:9875847

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