2x04

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Template:STRUCTURE 2x04

CRYSTAL STRUCTURE OF THE PABC-TNRC6C COMPLEX

Template:ABSTRACT PUBMED 20098421

About this Structure

2x04 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Jinek M, Fabian MR, Coyle SM, Sonenberg N, Doudna JA. Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation. Nat Struct Mol Biol. 2010 Feb;17(2):238-40. Epub 2010 Jan 24. PMID:20098421 doi:10.1038/nsmb.1768
  • Tritschler F, Huntzinger E, Izaurralde E. Role of GW182 proteins and PABPC1 in the miRNA pathway: a sense of deja vu. Nat Rev Mol Cell Biol. 2010 May;11(5):379-84. Epub 2010 Apr 9. PMID:20379206 doi:10.1038/nrm2885

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