3msj
From Proteopedia
Structure of bace (beta secretase) in complex with inhibitor
Template:ABSTRACT PUBMED 20656487
About this Structure
3MSJ is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Madden J, Dod JR, Godemann R, Kraemer J, Smith M, Biniszkiewicz M, Hallett DJ, Barker J, Dyekjaer JD, Hesterkamp T. Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5329-33. Epub 2010 Jun 27. PMID:20656487 doi:10.1016/j.bmcl.2010.06.089
Page seeded by OCA on Wed Sep 1 09:21:31 2010
Categories: Homo sapiens | Memapsin 2 | Barker, J. | Godemann, R. | Kramer, J. | Madden, J. | Smith, M A. | Alzheimer's disease | Amyloid precursor protein secretase | Aspartic endopeptidase | Aspartic protease | Aspartyl protease | Base | Beta-secretase | Fluorescence polarisation | Fragment-based drug design | Glycoprotein | Hydrolase | Protease | Transmembrane | Zymogen