User:Rick H. Cote/PDE6

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PDE6 catalytic subunit partial structures

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    -- Crystal structure of the cGMP-bound GAF a domain from the photoreceptor phosphodiesterase 6C

    PDE5/PDE6 structures

    • 3jwq -- Crystal structure of chimeric PDE5/PDE6 catalytic domain complexed with sildenafil
    • 3jwr -- Crystal structure of chimeric PDE5/PDE6 catalytic domain complexed with 3-isobutyl-1-methylxanthine (IBMX) and PDE6 gamma-subunit inhibitory peptide 70-87

    PDE6 inhibitory gamma subunit structures

    • 2ju4 -- NMR structure of the gamma subunit of cGMP phosphodiesterase
    • 1fqj -- CRYSTAL STRUCTURE OF THE HETEROTRIMERIC COMPLEX OF THE RGS DOMAIN OF RGS9, THE GAMMA SUBUNIT OF PHOSPHODIESTERASE AND THE GT/I1 CHIMERA ALPHA SUBUNIT [(RGS9)-(PDEGAMMA)-(GT/I1ALPHA)-(GDP)-(ALF4-)-(MG2+)]

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    Rick H. Cote

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