3kxh

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Template:STRUCTURE 3kxh

Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor (2-dymethylammino-4,5,6,7-tetrabromobenzoimidazol-1yl-acetic acid (K66)

Template:ABSTRACT PUBMED 21513497

About this Structure

3kxh is a 1 chain structure with sequence from Zea mays. Full crystallographic information is available from OCA.

Reference

  • Sarno S, Papinutto E, Franchin C, Bain J, Elliott M, Meggio F, Kazimierczuk Z, Orzeszko A, Zanotti G, Battistutta R, Pinna LA. Atp Site-Directed Inhibitors of Protein Kinase Ck2: An Update. Curr Top Med Chem. 2011 Mar 29. PMID:21513497
  • Battistutta R, De Moliner E, Sarno S, Zanotti G, Pinna LA. Structural features underlying selective inhibition of protein kinase CK2 by ATP site-directed tetrabromo-2-benzotriazole. Protein Sci. 2001 Nov;10(11):2200-6. PMID:11604527
  • Battistutta R, Mazzorana M, Cendron L, Bortolato A, Sarno S, Kazimierczuk Z, Zanotti G, Moro S, Pinna LA. The ATP-binding site of protein kinase CK2 holds a positive electrostatic area and conserved water molecules. Chembiochem. 2007 Oct 15;8(15):1804-9. PMID:17768728 doi:10.1002/cbic.200700307

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