2y71

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Image:2y71.jpg

Template:STRUCTURE 2y71

STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS TYPE II DEHYDROQUINASE COMPLEXED WITH (1R,4S,5R)-1,4,5-TRIHYDROXY-3-((5-METHYLBENZO(B)THIOPHEN-2-YL)METHOXY)CYCLOHEX-2-ENECARBOXYLATE

Template:ABSTRACT PUBMED 21780742

About this Structure

2y71 is a 1 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  • Tizon L, Otero JM, Prazeres VF, Llamas-Saiz AL, Fox GC, van Raaij MJ, Lamb H, Hawkins AR, Ainsa JA, Castedo L, Gonzalez-Bello C. A Prodrug Approach for Improving Antituberculosis Activity of Potent Mycobacterium tuberculosis Type II Dehydroquinase Inhibitors. J Med Chem. 2011 Aug 3. PMID:21780742 doi:10.1021/jm2006063

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