2kqt

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Template:STRUCTURE 2kqt

Contents 1 Solid-state NMR structure of the M2 transmembrane peptide of the influenza A virus in DMPC lipid bilayers bound to deuterated amantadine 2 About this Structure 3 See Also 4 Reference

Solid-state NMR structure of the M2 transmembrane peptide of the influenza A virus in DMPC lipid bilayers bound to deuterated amantadine

Template:ABSTRACT PUBMED 20130653

About this Structure

2kqt is a 4 chain structure. Full experimental information is available from OCA.

See Also

• Amantadine

Reference

• Cady SD, Schmidt-Rohr K, Wang J, Soto CS, Degrado WF, Hong M. Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers. Nature. 2010 Feb 4;463(7281):689-92. PMID:20130653 doi:10.1038/nature08722
• Cady SD, Mishanina TV, Hong M. Structure of amantadine-bound M2 transmembrane peptide of influenza A in lipid bilayers from magic-angle-spinning solid-state NMR: the role of Ser31 in amantadine binding. J Mol Biol. 2009 Jan 30;385(4):1127-41. Epub 2008 Nov 24. PMID:19061899 doi:10.1016/j.jmb.2008.11.022
• Hu J, Asbury T, Achuthan S, Li C, Bertram R, Quine JR, Fu R, Cross TA. Backbone structure of the amantadine-blocked trans-membrane domain M2 proton channel from Influenza A virus. Biophys J. 2007 Jun 15;92(12):4335-43. Epub 2007 Mar 23. PMID:17384070 doi:biophysj.106.090183